Fig. 7
From: Effects of ATF2/TSC1 on epilepsy by modulating the microphages polarization of microglia
Overexpressed TSCI represses M1 polarization of KA-induced HMC3 cells. (A-B) TSC1 protein level in KA-stimulated HMC3 cells transfected with pcDNA-TSC1. (C-D) The relative expression of IBA1 protein. Flow cytometry detected the cell ratios of CD80 (E-F), IL-1β (G and J), CD206 (H and K), and CD163 (I and L). The relative expression of TNF-α (M), IL-6 (N), TGF-β (O), and IL-10 (P) mRNA. (Q) The gel images of INOS and ARG1. (R) Relative expression of INOS protein. (S) Relative expression of ARG1 protein. *P < 0.05, **P < 0.01, ***P < 0.001.
