Fig. 8

ATF2 regulates microglia polarization in KA-induced mouse by medicating TSC1 transcription. (A) Racine scale scores were used to evaluate the seizure severity of mice. (B) HE staining of mouse hippocampal tissues. (C-D) Nissl staining of mouse hippocampal tissues. (E) The gel images of ATF2 and TSC1. The relative expression of ATF2 (F) and TSC1 (G). (H-I) The fluorescence staining of IBA1 and CD80. (J-K) The fluorescence staining of IBA1 and CD206. The relative expression of TNF-α (L), IL-6 (M), TGF-β (N), and IL-10 (O). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.