Table 2 Multifactor logistic analysis for vascular injury in patients with T2DM.
From: Decreased PECAM-1 May be a potential pathological factor for vascular injury in T2DM patients
Variables | Non- Vascular injury (n = 36) | Vascular injury (n = 30) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |||
Age, mean (SD), y | 59.0 (10.4) | 58.4 (13.3) | 1.00 (0.96–1.04) | 0.838 | ||
Sex, n (%) | ||||||
Male | 25 (69.4%) | 20 (66.7%) | 0.88 (0.31–2.49) | 0.809 | ||
Female | 11 (30.6%) | 10 (33.3%) | ||||
HbA1c, mean (SD), % | 7.6 (3.1) | 11.5 (4.7) | 1.33 (1.12–1.58) | 0.001 | 1.32 (1.10–1.58) | 0.003 |
Cholesterol, mean (SD), mmol/L | 6.9 (3.3) | 6.8 (2.0) | 0.98 (0.82–1.17) | 0.798 | ||
Triglyceride, mean (SD), mmol/L | 0.8 (0.5) | 1.8 (0.8) | 1.09 (0.90–1.33) | 0.382 | ||
Hb, mean (SD), g/L | 130.0 (26.3) | 127.2 (30.5) | 1.00 (0.98–1.01) | 0.678 | ||
Plt, mean (SD), ×109/L | 204.1 (59.9) | 232.8 (105.9) | 1.00 (1.00-1.01) | 0.182 | ||
BMI, mean (SD), kg/m2 | 24.7 (2.6) | 23.9 (2.9) | 0.91 (0.75–1.09) | 0.288 | ||
PECAM-1, mean (SD), ng/mL | 20.1 (4.8) | 17.2 (4.6) | 0.86 (0.75–0.98) | 0.024 | 0.85 (0.73–0.99) | 0.037 |
Aerobic exercise, n (%) | 22 (61.1%) | 13 (43.3%) | 2.05 (0.77–5.50) | 0.152 | ||
Alcohol consumption, n (%) | 12 (33.3%) | 7 (23.3%) | 1.64 (0.55–4.90) | 0.374 | ||
Smoking, n (%) | 15 (41.7%) | 20 (66.7%) | 2.80 (1.02–7.67) | 0.045 | 2.64 (0.78–8.92) | 0.117 |
Hypertension, n (%) | 17 (47.2%) | 16 (53.3%) | 0.78 (0.30–2.07) | 0.621 | ||
