Table 2 Baseline bacterial characteristics of CRKp isolated from each patient at unique admissions.
From: A network analysis of carbapenem-resistant Klebsiella pneumoniae among healthcare facilities
Characteristics; n (%) | Total (n = 630) | Linked admission (n = 404) | Out of network (n = 226) | P value |
|---|---|---|---|---|
Culture source | – | |||
Blood | 102 (16) | 55 (14) | 47 (21) | |
Respiratory | 92 (15) | 65 (16) | 27 (12) | |
Urine | 341 (54) | 219 (54) | 122 (54) | |
Wound | 59 (9.4) | 42 (10) | 17 (7.5) | |
Other | 36 (5.7) | 23 (5.7) | 13 (5.8) | |
Multi-locus sequence type (MLST) | < 0.001 | |||
258 | 495 (79) | 353 (87) | 142 (63) | |
11 | 28 (4.4) | 19 (4.7) | 9 (4.0) | |
307 | 34 (5.4) | 17 (4.2) | 17 (7.5) | |
37 | 8 (1.3) | 3 (0.7) | 5 (2.2) | |
Other (\(\le\) 5 isolates per ST)a | 65 (10) | 12 (3.0) | 53 (24) | |
wzi type | < 0.001 | |||
154 | 322 (51) | 225 (56) | 97 (43) | |
173 | 36 (5.7) | 17 (4.2) | 19 (8.4) | |
29 | 175 (28) | 129 (32) | 46 (20) | |
27 | 29 (4.6) | 19 (4.7) | 10 (4.4) | |
Other (\(\le\) 5 isolates per type)b | 68 (11) | 14 (3.5) | 54 (24) | |
bla carbapenemase | ||||
KPC-2 | 281 (45) | 175 (43) | 106 (47) | – |
KPC-3 | 332 (53) | 225 (56) | 107 (47) | 0.046 |
NDM-1 | 5 (0.8) | 2 (0.5) | 3 (1.3) | – |
NDM-5 | 2 (0.3) | 0 (0) | 2 (0.9) | – |
OXA-181 | 1 (0.2) | 0 (0) | 1 (0.4) | – |
OXA-48 | 2 (0.3) | 0 (0) | 2 (0.9) | – |
OXA-232 | 26 (4.1) | 16 (4.0) | 10 (4.4) | – |
bla extended spectrum β-lactamase | ||||
SHV-12 | 244 (39) | 176 (44) | 68 (30) | < 0.001 |
SHV-28 | 38 (6.0) | 16 (4.0) | 22 (9.7) | 0.005 |
SHV-7 | 3 (0.5) | 0 (0) | 3 (1.3) | 0.046 |
CTX-M-14 | 4 (0.6) | 2 (0.5) | 2 (0.9) | – |
CTX-M-15 | 100 (16) | 53 (13) | 47 (21) | 0.013 |
