Fig. 5

Effects of the combination of radiation and WA on GC cell bioenergetics. (A) The oxygen consumption rate (OCR) in SGC-7901 cells exposed to WA (20 µM) or bafilomycin (10 nM) and 10 Gy radiation was determined by a mitochondrial stress test. (B-G) ATP-linked, maximal, reserve capacity, proton leakage, and nonmitochondrial OCR were calculated from (A) as described in the Methods. The data are the mean and SD of three independent repeats. All the results were shown as mean ± SD (n = 3). *P < 0.05, **P < 0.01 and ***P < 0.001.