Fig. 6

The combination of WA and radiation increases the radiosensitivity of gastric cancer cells in vivo. Xenografts were established in nude mice to examine whether WA can increase the radiosensitivity of gastric cancer in vivo. Each group of mice was composed of three male nude mice. Tumour sizes were measured at 2-day intervals. (A) There was no difference between the PBS group and the WA group. However, gastric cancer cell growth was effectively suppressed in the combined treatment group compared with the 10 Gy X-ray irradiation group. (B) Tumour xenografts from each group. (C) The weights of tumours collected immediately after sacrifice on day 21. Three representative tumor samples were shown per group although five mice were used in each group. All the results were shown as mean ± SD (n = 5). *P < 0.05, **P < 0.01 and ***P < 0.001.