Table 2 Univariate logistics regression analysis of all patients on 28-day mortality.

From: The association between ionized calcium level and 28-day mortality in patients with sepsis: a cohort study

Variables

28-Day mortality

OR 95% CI P-value

Gender

 Male

Reference

 Female

0.99 (0.82, 1.19) 0.9081

Age (year)

1.01 (1.01, 1.02) < 0.0001

BMI (kg/m2)

0.98 (0.97, 0.99) 0.0018

Ethnicity

 Caucasian

Reference

 African American

1.01 (0.76, 1.34) 0.9450

 Hispanic

0.94 (0.51, 1.73) 0.8427

 Asian

1.17 (0.64, 2.12) 0.6153

 Native American

1.20 (0.35, 4.12) 0.7693

 Other/Unknown

1.42 (0.95, 2.10) 0.0843

Site of infection recoded

 Pulmonary

Reference

 Renal/UTI (including bladder)

0.64 (0.46, 0.90) 0.0109

 GI

1.16 (0.83, 1.61) 0.3815

 Unknown

1.04 (0.83, 1.30) 0.7637

 Cutaneous/soft tissue

0.57 (0.35, 0.93) 0.0250

 Other

1.01 (0.65, 1.56) 0.9716

 Gynercologic

1.06 (0.13, 8.84) 0.9599

 SOFA score

1.23 (1.19, 1.26) < 0.0001

 APACHE IV score

1.03 (1.03, 1.04) < 0.0001

 Temperature (℃)

0.84 (0.79, 0.90) < 0.0001

 Heart rate (bpm)

1.01 (1.00, 1.01) 0.0156

 Respiratory rate (bpm)

1.01 (1.00, 1.01) 0.0265

 MAP (mmHg)

1.00 (1.00, 1.00) 0.8074

 pH

0.04 (0.02, 0.10) < 0.0001

 PaO2 (mmHg)

1.00 (1.00, 1.00) 0.0055

 PaCO2 (mmHg)

1.00 (0.99, 1.00) 0.3403

 Lactate (mmol/L)

1.22 (1.18, 1.26) < 0.0001

 WBC (K/uL)

1.01 (1.00, 1.02) 0.0017

 Hemoglobin (g/dL)

0.98 (0.94, 1.02) 0.2381

 Platelets(K/uL)

1.00 (1.00, 1.00) 0.0001

 Total bilirubin (mg/dL)

1.10 (1.07, 1.13) < 0.0001

 Albumin (g/dL)

0.61 (0.53, 0.71) < 0.0001

 Glucose (mg/dL)

1.00 (1.00, 1.00) 0.8369

 BUN (mg/dL)

1.01 (1.00, 1.01) 0.0003

 Creatinine (mg/dL)

1.06 (1.01, 1.10) 0.0150

 Sodium (mmol/L)

1.00 (0.98, 1.01) 0.6739

 Potassium (mmol/L)

1.10 (0.99, 1.23) 0.0818

 Chloride (mmol/L)

1.00 (0.99, 1.01) 0.9479

 Ionized calcium (mg/dL)

0.67 (0.56, 0.79) < 0.0001

MV

 No

Reference

 Yes

3.53 (2.89, 4.31) < 0.0001

Dialysis

 No

Reference

 Yes

2.40 (1.91, 3.02) < 0.0001

Vasopressor

 No

Reference

 Yes

1.64 (1.29, 2.09) < 0.0001

Calcium gluconate/calcium chloride

 No

Reference

 Yes

1.29 (0.89, 1.86) 0.1773

Septic shock

 No

Reference

 Yes

1.57 (1.25, 1.98) 0.0001

COPD

 No

Reference

 Yes

1.09 (0.87, 1.37) 0.4343

Diabetes

 No

Reference

 Yes

0.83 (0.67, 1.04) 0.1080

Hypertension

 No

Reference

 Yes

0.87 (0.72, 1.04) 0.1326

CHF

 No

Reference

 Yes

0.93 (0.75, 1.17) 0.5510

MI

 No

Reference

 Yes

0.88 (0.65, 1.19) 0.3960

CKD

 No

Reference

 Yes

1.44 (1.09, 1.90) 0.0107

Cirrhosis

 No

Reference

 Yes

2.23 (1.60, 3.10) < 0.0001

Cancer

 No

Reference

 Yes

1.35 (1.08, 1.67) 0.0071

PE

 No

Reference

 Yes

1.30 (0.83, 2.04) 0.2451

Stroke

 No

Reference

 Yes

1.37 (1.06, 1.77) 0.0153