Fig. 5

Retinal degeneration in aged marmosets. (a) Fundus photo of a marmoset. The fundus was divided into the superior (S), inferior (I), temporal (T), and nasal (N) quadrants, with the optic disc at the center. (b) In vivo imaging of the retina. GCC: ganglion cell complex. (c) Quantification of the thickness of GCC in the temporal (T), superior (S), nasal (N), inferior (I) and temporal (T) retina measured by OCT. (d) Quantification of the averaged thickness of GCC in the whole measured retina region. (e) Quantification of the averaged thickness of the outer retina measured by OCT. n = 10 from both eyes of 5 young marmosets in (c), (d) and (e). n = 8 from both eyes of 4 aged marmosets in (c) and (d), and 6 from both eyes of 3 aged marmosets in (e). *P < 0.05, **P < 0.01 (Mann–Whitney U test). Data are expressed as the mean ± S.E.M.