Fig. 8 | Scientific Reports

Fig. 8

From: Unveiling the mechanisms and promising molecular targets of curcumin in pancreatic cancer through multi-dimensional data

Fig. 8

Analysis of Molecular Characteristics and Immune Microenvironment of DEHGs Subtypes. (A) Volcano plot displaying differentially expressed genes between the two subtypes, with red representing upregulated genes and blue representing downregulated genes. (B) Heatmap of gene expression, demonstrating clustering of samples into two distinct subtypes. (C) GO enrichment analysis of biological processes involved in each subtype. (D) Top 20 enriched pathways between the subtypes, showing significant involvement of immune and metabolic pathways. (E) Consensus clustering CDF curve and delta area plot, identifying the optimal number of clusters (K = 2). (F) PCA plot displaying the separation between the two subtypes. (G) Expression patterns of DEGs and DEHGs in clusters CI and CII. (H) Box plot showing differential expression analysis of DEHG scores between DEG clusters. (I) Box plot displaying differential expression analysis of DEHG scores between DEHG clusters. (J) Alluvial diagram illustrating the correspondence between different sample clusters.

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