Fig. 5 | Scientific Reports

Fig. 5

From: Deciphering the angiogenic potential of Zhishi Xiebai Guizhi decoction in coronary heart disease: an in-depth network pharmacology and experimental investigation

Fig. 5

The administration of ZXGD resulted in increased angiogenesis on HUVECs, contributing to the establishment of the OGD/R model. (A, C) Evaluation of relative cell migration area demonstrated a significant enhancement in HUVEC migration upon treatment with ZXGD (75 μm/L). All experiments were conducted in triplicate, and the data are presented as mean ± S.E.M. (B) Cell viability assays revealed the non-toxic nature of ZXGD on cells, with the highest viability observed at 75 μm/L. (D, E) Representative images of tube formation along with corresponding magnified views were captured for quantitative analysis of total tube length. n = 3 * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Scale bar = 100 μm.

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