Fig. 3
From: Corticothalamic feedback locally modulates network state
Sham correction for infra-slow oscillation (a,b) Spontaneous alternations of light and deep sleep epochs on the wavelet spectrum (a), and sigma and delta power (b) recurring every ~ 50 s. (c) Local field potential and smoothed multiunit activity during a transition (gray patch on panel (‘b’) from light to deep sleep. Green patches: spindles, orange patches: delta waves. (d) Analysis of prolonged stimulation data during infra-slow oscillation. The stimulus in this figure is for illustrative purposes only. Trials classified as light sleep in the baseline period were selected for the analysis. Baseline (gray line) period is compared to stimulated period (red line), omitting the stimulus onset. The stimulation causes a marked decrease in sigma power (d, e top). However, the spontaneous change from light to deep sleep also causes a decrease in sigma power (d, e bottom, sham stimulus). Traces are normalized to baseline. (f) Power difference between baseline for actual stimulation (solid line) and sham stimulation (dotted line). (g) In this example sigma power decrease in response to the stimulus is still significant after sham correction.
