Fig. 5 | Scientific Reports

Fig. 5

From: Corticothalamic feedback locally modulates network state

Fig. 5

Tonic corticothalamic activation induces deep sleep (a) Example trials and mean wavelet of cortical LFP with prolonged weak tonic stimulation (300 Hz, 4 mW) during light sleep. Note the disappearance of sleep spindles during the stimulus. (b) Power spectra before and during stimulation for all four sleep stages (pooled data of 8 animals). (c) Relative sigma power during stimulation compared to sham stimuli in light (top) and deep sleep (bottom). (d) Mean EMG and camera-recorded motion show no apparent behavioral change during the stimulus. (e) Example trace (top), rastergram and PSTH (bottom) of a juxtacellularly recorded L6CT cell to a similar stimulus. Wavelet spectrum on (a) is 1/f normalized.

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