Fig. 6
From: Corticothalamic feedback locally modulates network state
High intensity corticothalamic stimulation induces desynchronized state. (a) Representative cortical LFP traces before and during stimulation (300 Hz, 5.26 mW). Note the disappearance of both delta waves and spindles, as well as the enhanced gamma activity during the stimulus. (b) The effect is significant across all four states of alertness (pooled data of 7 animals). (c) Delta, sigma, and gamma RMS changes throughout the time course of the stimulus. (d) Mean EMG and camera-recorded motion show no apparent behavioral change during the stimulus. (e) Response of a juxtacellularly recorded L6CT cell to the stimulus used in this protocol. Wavelet spectrum on (a) is 1/f normalized.
