Table 2 5-HT levels and related gene transcription levels in the rat intestinal and brain.

Serum

5-HT (ng/ml)

424.77 ± 14.44

468.25 ± 18.88^a

455.64 ± 14.50^ac

359.97 ± 17.32^a

388.60 ± 22.87^a

460.19 ± 22.74

430.68 ± 13.75^c

Intestinal

5-HT (%)

11.70 ± 0.35

3.59 ± 1.25^a

4.98 ± 1.58^c

1.46 ± 0.82^a

11.17 ± 3.62

9.04 ± 1.41^b

12.44 ± 2.78^c

Vdr (2^−△△CT)

1.0092 ± 0.0114

0.4952 ± 0.2029^a

0.8865 ± 0.1489^ac

0.4060 ± 0.2933^ab

0.9610 ± 0.1396

0.9830 ± 0.1792^b

0.9949 ± 0.1725^c

Tph1 (2^−△△CT)

1.0050 ± 0.0034

0.5124 ± 0.1711^a

0.6592 ± 0.0496^ac

0.2141 ± 0.0375^ab

0.9506 ± 0.2092

0.9605 ± 0.0587^b

0.8436 ± 0.0860^c

Tph2 (2^−△△CT)

1.0033 ± 0.0030

0.5246 ± 0.1793^a

0.6740 ± 0.0633^ac

0.2312 ± 0.0745^a

1.0575 ± 0.0797

0.9807 ± 0.0626^b

0.8503 ± 0.0831^c

Ahr (2^−△△CT)

1.0058 ± 0.1315

2.0616 ± 0.1776^a

4.4813 ± 0.1648^ac

1.5362 ± 0.0146^ac

1.0394 ± 0.2751

1.3541 ± 0.0574^b

1.3541 ± 0.0574^c

Brain

5-HT (ng/ml)

66.93 ± 8.66

20.89 ± 5.29^a

47.23 ± 6.2 ^ac

15.07 ± 3.83^a

63.63 ± 11.38

48.55 ± 12.49^b

65.03 ± 6.94^c

Vdr (2^−△△CT)

1.0192 ± 0.0198

0.5009 ± 0.1516^a

0.8141 ± 0.1638^c

0.4561 ± 0.2893^a

1.1616 ± 0.3438

1.2543 ± 0.4093^b

1.1553 ± 0.5571^c

Tph2 (2^−△△CT)

1.0068 ± 0.0069

0.5521 ± 0.1956^a

0.7877 ± 0.1955^c

0.3620 ± 0.1592^a

1.0902 ± 0.2413

1.1070 ± 0.3387^b

0.9827 ± 0.2458^c