Fig. 5

RGLS inhibits fatty acid metabolism. (A) Effect of RGLS on ATP content in S-180 cells. (B–D) Effect of RGLS on the expression of Acsl families (B), Cpt1a (C), and Cat2 (D) in tumor tissue. (E) Effect of RGLS on L-carnitine content in S-180 cells. (F–G) Effect of RGLS on long-chain Acylcarnitine (F) and short-, and medium-chain Acylcarnitine (G) content in S-180 cells. (H) Effect of RGLS on the composition of fatty acid pool in S-180 cells. *P < 0.05, **P < 0.01, ***P < 0.001 compared with Con or Model group, n = 3.