Fig. 2 | Scientific Reports

Fig. 2

From: Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging

Fig. 2

ITPP improved CT26 tumor immunogenicity. (a) A study timeline. ITPP was administered on Day 12, then PAI was performed 3 h later, and then immediately followed by tumor harvest for cell analysis. The correlation between the frequencies of %sO2 and (b) CD4 + FoxP3-TCRb + CD45 + /live cells, (c) CD8 + TCRb + CD45 + /live cells, or (d) Ly6C + CD11b + CD45 + /live cells in CT26 tumors three hours after the ITPP treatment on Day 12. Dotted lines represent the 95% confidence interval while the solid lines represent the linear best fit line. n = 9–10.

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