Fig. 5 | Scientific Reports

Fig. 5

From: Potentiation of immune checkpoint blockade with an ITPP radiosensitizer studied with oxygen saturation measurements from photoacoustic imaging

Fig. 5

ITPP improved 4T1 tumor immunogenicity. (a) A study timeline. ITPP was administered on Day 10, then PAI was performed 3 h later, and then immediately followed by tumor harvest for cell analysis. The correlation between the frequencies of %sO2 and A) CD4 + FoxP3-TCRb + CD45 + /live cells, (b) CD8 + TCRb + CD45 + /live cells, or (c) Ly6C + CD11b + CD45 + /live cells in 4T1 tumors three hours after the ITPP treatment on Day 10. Dotted lines represent the 95% confidence interval while the solid lines represent the linear best fit line. n = 8–10.

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