Table 4 Paddle method parameters – buffer stage.

From: In vitro evaluation of mesalazine enteric-coated tablet dissolution by the reciprocating cylinder method

Apparatus parameter

Paddle conditions

Speed

50 rpm

Medium

pH 6.8

Volume

900 ml

Filter

10 μm

Aliquot volume

10 ml

Temperature

37 °C ± 0.5 °C

Sampling time points

5, 10, 15, 30, 45, 60, and 90 min

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