Table 2 Modified o’driscoll scoring for cartilage repairing evaluation.

From: Bioinformatic prediction of key genes involved in pro-chondrogenic effect of fragmentated cartilage transplantation

Dimensions

Points

% Hyaline in repaired tissue

≤ 20% (0), 21–40% (2), 41–60% (4), 61–80% (6), > 80% (8)

Structural characteristics

Surface irregularity

Severe degeneration (0), fissures (1), smooth and intact (2)

Structural integrity

Severe lack of integration (0), slight disruption including cysts (1), normal (2)

Thickness

≤ 50% (0), 51–99% (1), 100% (2) of normal adjacent cartilage

Integration to surrounding cartilage

Not integration (0), integrated at 1 end/partially at both ends (1), integrated at both ends of graft (2)

Cellular degeneration in repaired tissue (degreed of hypocellularity)

> 25% chondrocyte clusters (0); ≤25% clusters (1); no clusters (2)

Degeneration in adjacent tissue

Severe hypocellularity, slight staining (0); mild hypocellularity, slight staining (1); normal cellularity, mild clusters, moderate staining (2); normal cellularity, no clusters, normal staining (3)

Reconstitution of subchondral bone

≤ 50% (0), 51–100% (1), complete reconstitution (2)

Integration of repaired cartilage to de novo subchondral bone

≤ 50% (0), 51–100% (1), complete and uninterrupted (2)

Safranin O staining

≤ 40% (0), 41–80% (1), > 80% (2)