Fig. 1
Expression of protein kinase R (PKR) in pancreatic ductal adenocarcinoma (PDAC) tissue and association with disease-free survival (DFS). Expression and clinical significance of PKR in various cancers, particularly PDAC. (a) Transcript expression profile of PKR across various tumor types compared to normal tissues. Transcripts per million (TPM) were used as units of expression. The height of the bar represents the median expression of certain tumor type or normal tissue. Red bars represent tumor tissues, whereas gray bars represent normal tissues. (b) PKR mRNA level was much higher in patients with pancreatic cancer than in healthy individuals (P < 0.01). (c) Kaplan–Meier survival curves showing the clinical significance of PKR expression in patients with PDAC. The panel shows DFS. Patients were divided into high (red curve) and low (gray curve) PKR expression groups.
