Table 3 Association of the accumulation of STR alterations with clinicopathological characteristics of HCC.
From: Evaluation of genetic instability of short tandem repeats in hepatocellular carcinoma
Characteristics | n | No. of the accumulation of STR alterations | p-value | ||
|---|---|---|---|---|---|
The stable group (n = 0) | The low-alterated group (n = 1 ~ 2) | The hihg-alterated group (n ≥ 3) | |||
Age | 0.064 | ||||
≥ 60 | 50 | 8 | 15 | 27 | |
< 60 | 51 | 13 | 6 | 32 | |
Sex | 0.438 | ||||
Female | 17 | 2 | 5 | 10 | |
Male | 84 | 19 | 16 | 49 | |
Tumor size | 0.154 | ||||
≥ 5 cm | 58 | 8 | 13 | 37 | |
< 5 cm | 43 | 13 | 8 | 22 | |
Tumor number | 0.224 | ||||
Single | 71 | 14 | 18 | 39 | |
Multiple | 30 | 7 | 3 | 20 | |
AFP (ng/ml) | 0.287 | ||||
≥ 20 ng/ml | 58 | 12 | 9 | 37 | |
< 20 ng/ml | 43 | 9 | 12 | 22 | |
Hepato-cirrhosis | 0.291 | ||||
Positive | 13 | 2 | 5 | 6 | |
Negative | 88 | 19 | 16 | 53 | |
HBsAg | 0.049 | ||||
Positive | 83 | 16 | 14 | 53 | |
Negative | 18 | 5 | 7 | 6 | |
Degree of differentiation | 0.020 | ||||
Well /well-moderate | 35 | 8 | 12 | 15 | |
Moderate-poor /poor | 66 | 13 | 9 | 45 | |
