Table 2 The selectivity index (SI) values of the tested essential oils against influenza A/H1N1 and A/H5N1, and SARS-CoV-2 viruses.

From: In vitro antiviral activities of thymol and Limonin against influenza a viruses and SARS-CoV-2

Essential Oil

Virus

CC50 (mg/ml)

IC50 (µg/ml)

SI

Citations

Thymol

H1N1

1.59

0.022

> 100

This study

H5N1

0.0156

> 100

SARS-CoV-2

0.0632

0.59

< 100

Limonin

H1N1

6.72

4.25

> 100

H5N1

0.0185

> 100

SARS-CoV-2

< 10

4.04

< 100

Camphor

H1N1

< 10

234.1

42.7

Peppermint oil

H1N1

5.23

IC50 < CC50

N/A

Eucalyptus oil

H1N1

10.01

IC50 < CC50

N/A

Clove oil

H1N1

< 10

IC50 < CC50

N/A

Zanamivir

H1N1

< 10

0.792

> 100

71

H5N1

0.265

> 100

Remdesivir

SARS-CoV-2

0.473

6.721

70.40

72