Fig. 2 | Scientific Reports

Fig. 2

From: TIGAR regulated by HPV E6 is correlated with disease stage, drug sensitivity, and immune microenvironment in cervical cancer

Fig. 2

Expression, ROC curve and survival analysis of TIGAR in cervical cancer in TCGA and GTEx. (A) TIGAR mRNA levels in pan-cancer using TCGA and GTEx datasets. ACC, Adrenocortical carcinoma; BLCA, Bladder Urothelial Carcinoma; BRCA, Breast invasive carcinoma; CESC, Cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL, Cholangiocarcinoma; COAD, Colon adenocarcinoma; DLBC, Lymphoid Neoplasm Diffuse Large B-cell Lymphoma; ESCA, Esophageal carcinoma; GBM, Glioblastoma multiforme; HNSC, Head and Neck squamous cell carcinoma; KICH, Kidney Chromophobe; KIRC, Kidney renal clear cell carcinoma; KIRP, Kidney renal papillary cell carcinoma; LAML, Acute Myeloid Leukemia; LGG, Brain Lower Grade Glioma; LIHC, Liver hepatocellular carcinoma; LUAD, Lung adenocarcinoma; LUSC, Lung squamous cell carcinoma; MESO, Mesothelioma; OV, Ovarian serous cystadenocarcinoma; PAAD, Pancreatic adenocarcinoma; PCPG, Pheochromocytoma and Paraganglioma; PRAD, Prostate adenocarcinoma; READ, Rectum adenocarcinoma; SARC, Sarcoma; SKCM, Skin Cutaneous Melanoma; STAD, Stomach adenocarcinoma; TGCT, Testicular Germ Cell Tumors; THCA, Thyroid carcinoma; THYM, Thymoma; UCEC, Uterine Corpus Endometrial Carcinoma; UCS, Uterine Carcinosarcoma; UVM, Uveal Melanoma. Cervical cancer data is circled by a red box. (B) TIGAR mRNA levels in cervical cancer tissues and normal cervical tissues from TCGA and GTEx datasets. (C) Diagnostic value of TIGAR in cervical cancer. (D) Kaplan–Meier survival curves was estimated based on TIGAR high expression (red) and low expression (green) in cervical cancer tissues in TCGA datasets using GEPIA2. *P < 0.05; **P < 0.01; ***P < 0.001.

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