Table 3 Stratified analysis of change in total point score and mean deviation in pseudophakia eyes.

From: Post hoc analysis of a randomized placebo-controlled trial suggests potential visual benefits of branched-chain amino acids in retinitis pigmentosa

 

TK-98 (7 patients, 12 eyes)

Placebo (10 patients, 17 eyes)

Intergroup comparison

Least-squares mean ± SE

Median (range)

Least-squares mean ± SE

Median (range)

Difference in least-squares mean

P value

Total point score (10-2) (dB/year)

− 45.0 ± 24.0

− 17.8 (− 183.6, 31.6)

− 48.6 ± 20.1

− 66.1 (− 127.5, 113.4)

3.6 (− 63.1, 70.4)

0.909

MD (10-2) (dB/year)

− 0.63 ± 0.36

− 0.22 (− 2.63, 0.49)

− 0.72 ± 0.30

− 0.89 (− 2.00, 1.72)

0.09 (− 0.91, 1.10)

0.846

  1. The least squares mean is the mean of each group estimated in a mixed-effects model that accounts for binocular correlation. Intergroup comparisons are shown as intergroup differences in the least-squares means between TK-98 and placebo (95% confidence interval). Total point score was calculated as the sum of visual sensitivities for all measured locations. SE standard error, dB decibel, MD mean deviation.
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