Table 3 The percentages of relative cytochrome P450 gene expression in THLE-3 after treatments at the concentration of 50 µg/mL for 48 h, normalized by β-actin.

From: Barleria extracts containing barlerin and verbascoside boost immunity and regulate CYP450 gene in prostate cancer

Condition

% Relative gene expression

CYP1A2

CYP2A6

CYP3A4

CYP2D6

CYP2E1

DMSO

100.00 ± 0.00a

100.00 ± 0.00a

100.00 ± 0.00a

100.00 ± 0.00a

100.00 ± 0.00a

B. cristata

74.54 ± 0.70b

103.24 ± 0.53a

87.80 ± 2.10a

46.29 ± 1.56b

70.72 ± 4.67b

B. siamensis

59.19 ± 0.67b

72.00 ± 0.72b

46.63 ± 0.65b

27.75 ± 0.59b

59.96 ± 0.88b

B. strigosa

119.53 ± 0.89a

133.75 ± 2.80b

103.10 ± 0.75a

77.29 ± 0.74b

158.81 ± 2.43b

Barlerin

94.69 ± 0.96a

102.45 ± 1.51a

81.01 ± 3.94a

54.07 ± 2.94b

116.22 ± 1.75a

Verbascoside

82.23 ± 0.87a

90.14 ± 2.65a

82.87 ± 0.75a

38.38 ± 1.74b

84.63 ± 4.46a

  1. All data was represented in mean ± S.D. a = p-value > 0.05, b = p‐value < 0.0001, which is compared to DMSO as a control.