Fig. 3

Qualitative and Quantitative Expression Analysis of GR and Its Isoforms Alpha and Beta in PBMCs of Septic Patients. A Immunofluorescence depiction of overall GR protein (green dots) alongside actin filaments, stained with phalloidin (red). B Quantitative mRNA expression of GR and its isoforms, alpha and beta. While no significant differences in overall GR expression are observed between patients possessing TT and CC/CT genotypes of the rs6198 SNP, there is a significant increase in GRα expression associated with the TT genotype.