Fig. 2
From: Macrophage induces angiogenesis via HIF signaling in denervated muscle following nerve injury
Neurodegeneration Activates Endothelial Cells in Denervated Muscle. (A) mRNA expression levels of Vcam, Icam, and Selectin in the contralateral or ipsilateral lumbrical muscle at PO Day 3. ****P<0.001, ***P<0.005, by unpaired t-test. (B) Representative images showing td-Tomato expression (red) and immunostaining of CD105 or collagen IV (green) in contralateral and ipsilateral TA muscles of Tie2-Tomato mice at PO day 3. (C) mRNA expression levels of Agp2, Pgf, Pdgfβ, Mmp2, and Mmp3 in the contralateral or ipsilateral lumbrical muscle at PO day 3. ****P<0.001, ***P<0.005, **P<0.01, by unpaired t-test.
