Fig. 1
From: Sleep patterns, plasma metabolites, and risk of incident osteoarthritis: a prospective cohort study

Overview of the study design and participant selection. A total of 325,513 participants were included in the analysis of associations between sleep traits and OA risk. Of these, 169,877 participants with available metabolic data were included in the subsequent analysis investigating the effect of sleep-related metabolic profile on OA risk. Abbreviation: OA, osteoarthritis.