Fig. 2
From: CRISPR-Cas9 screening identifies a gene signature predictive of prognosis in glioblastoma
Identification of proliferation-related essential genes and pathways in glioblastoma using CRISPR-based loss-of-function screening. (a) Hallmark pathway enrichment analysis of glioblastoma proliferation-related essential genes based on CERES scores. (b) Top 5 hallmark pathways ranked by NES. (c) GO enrichment analysis of the identified proliferation-related essential genes. (d) KEGG pathway enrichment analysis of proliferation-related essential genes. NES normalized enrichment scores, GO gene ontology, KEGG kyoto encyclopedia of genes and genomes, BP biological process, CC cell component, MF molecular function.
