Fig. 4
From: CRISPR-Cas9 screening identifies a gene signature predictive of prognosis in glioblastoma
Validation of the proliferation-related essential genes prognostic signature in internal and external cohorts. (a) Distribution of risk scores (top), survival status (middle), and expression levels of the five signature genes (bottom) in glioblastoma patients across two internal cohorts (TCGA-test and TCGA-entire) and four external cohorts (CGGA-325, CGGA-693, GSE74187, GSE83300). (b) Kaplan-Meier survival curves for internal and external cohorts, showing significantly poorer overall survival in the high-risk group compared to the low-risk group. (c) ROC curves demonstrating the predictive performance of the prognostic signature in each cohort. TCGA the cancer genome atlas, CGGA Chinese glioma genome atlas, ROC receiver operating characteristic, AUC area under curve.
