Fig. 9
From: CRISPR-Cas9 screening identifies a gene signature predictive of prognosis in glioblastoma
Correlation between the proliferation-related essential genes signature and drug sensitivity. (a) Scatter plots showing the negative correlation between the risk score and IC50 values for several drugs, including Denileukin Diftitox Ontak, Vorinostat, Entinostat, Quisinostat, AFP464, Tipifarnib, JZL-195, Ixabepilone, and RO-5,126,766. (b) Boxplots comparing IC50 values for the above drugs between high-risk and low-risk groups. Statistical significance: *p < 0.05. IC50 half maximal inhibitory concentration.
