Fig. 2

Metabolomics QC sample evaluation graphs in positive and negative ion modes, and PLS-DA score graphs for the control group and HT group. (A,B) QC sample evaluation graphs in positive and negative ion modes, respectively; the horizontal axis is the RSD (%) value, i.e., standard deviation/mean, and the vertical axis is the cumulative proportion of ion peaks. (C) PLS-DA score graphs for the control group and HT group in positive ion mode. (D) 7-fold cross-validation and response permutation tests of PLS-DA in positive ion mode. (E) PLS-DA score graphs for the control group and HT group in negative ion mode. (F) 7-fold cross-validation and response permutation tests of PLS-DA in negative ion mode.