Fig. 16 | Scientific Reports

Fig. 16

From: Synthesis, comprehensive in silico studies, and cytotoxicity evaluation of novel quinazolinone derivatives as potential anticancer agents

Fig. 16

BOILED-Egg plot depicting the passive gastrointestinal absorption (HIA, white region) and blood-brain barrier (BBB, yellow region) penetration potential of quinazolinone derivatives. Each point represents a molecule plotted by its WLOGP and TPSA values. Blue circles indicate predicted P-gp substrates (PGP+), while red circles indicate non-substrates (PGP−). One compound lies outside the ideal absorption/permeability space, suggesting limited bioavailability.

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