Table 2 HIV-1 Inhibition concentration (IC50) on TZM-Bl cells for Penicillium Rubens P03MB2 extracts obtained from oat media.

From: Combining an OSMAC approach and untargeted metabolomics to profile compounds exhibiting anti-HIV-1 activities in an endophytic fungus, Penicillium Rubens P03MB2

Penicillium rubens P03MB2 fractions (Oats media)

IC50 (µg/mL)

HIV inhibition %

Oats MAX crude extracts

158,4893

54

Oats MAX 5%

Not converged

49

Oats MAX 45%

0,7063

91

Oats MAX 95%

3.843e + 015

91

Oats MCX crude extracts

0,0446

88,5

Oats MCX 5%

0,0316

96,5

Oats MCX 45%

0,0208

95,5

Oats MCX 95%

0,0001169

71,5

AZT

0,002407

101

  1. *Eluted in 5%, 45%, and 95% methanol; not converged (no sigmoid shape), could not determine IC50.
Back to article page