Fig. 5

Linear and nonlinear relationship analysis via the RCS. RCS, restricted cubic spline; KD, kidney dysfunction; IL, interleukin; IFN, interferon; TNF, tumor necrosis factor. (A) RCS curve between IL6 and kidney dysfunction, presenting a linear relationship; (B) RCS curves between IL12P70 and kidney dysfunction, presenting a nonlinear relationship of U shape; (C) RCS curve of IL17 for dyslipidemia, presenting a nonlinear relationship of n shape; (D) RCS curve of IL10 for malnutrition, without a linear or nonlinear relationship.