Table 1 Basic information and laboratory test data of the participants.

Male/female (n/n) *

32/19

28/25

61/24

Age (years old)

58.4 ± 11.4

55.4 ± 11.4

59.0 ± 11.3

TP (g/L)

71.11 ± 3.57

64.13 ± 6.61^a

67.98 ± 8.31^{a, b}

Alb (g/L)

44.43 ± 3.05

35.83 ± 5.29^a

35.95 ± 5.40^a

Ure (mmol/L)

5.21 ± 1.41

7.39 ± 2.10^a

8.54 ± 2.79^{a, b}

Cre (µmol/L)

63.3 ± 15.2

105.2 ± 21.6

108.0 ± 88.5^{a, b}

CysC (mg/L)

0.94 ± 0.14

0.91 ± 0.15

1.57 ± 1.35^{a, b}

GFR (ml/min/1.73m²)

91.9 ± 13.7

106.4 ± 21.9^a

64.1 ± 23.8^{a, b}

T-Chol (mmol/L)

4.09 ± 0.74

4.24 ± 0.94

5.08 ± 1.89^{a, b}

TG (mmol/L)

0.99 ± 0.33

1.70 ± 0.92^a

2.29 ± 1.15^{a, b}

HDL-Chol (mmol/L)

1.50 ± 0.35

1.07 ± 0.19^a

1.11 ± 0.40^a

LDL-Chol (mmol/L)

2.45 ± 0.99

2.74 ± 0.89

3.04 ± 1.61^a

Glu (mmol/L)

5.03 ± 0.53

6.19 ± 2.63^a

7.53 ± 2.23^{a, b}

HbA1c (%)

5.6 ± 0.3

8.2 ± 2.5^a

9.0 ± 1.7^a

IL1β (ng/L)

1.16 (0.96, 2.22)

1.76 (0.80, 2.18)

1.93 (1.01, 3.10)

IL2 (ng/L)

2.85 (2.18, 3.34)

1.91 (0.43, 3.41)^a

0.76 (0.45, 1.29)^{a, b}

IL4 (ng/L)

2.15 (1.64, 2.46)

1.39 (0.56, 2.64)^a

0.80 (0.55, 1.66)^a

IL5 (ng/L)

0.78 (0.67, 0.97)

0.99 (0.26, 1.27)

0.58 (0.46, 1.22)

IL6 (ng/L)

2.98 (2.25, 3.66)

9.04 (4.19, 28.74)^a

30.41 (7.88, 64.85)^{a, b}

IL8 (ng/L)

11.01 (8.03, 15.53)

16.94 (9.33, 20.40)^a

22.40 (15.89, 33.26)^{a, b}

IL10 (ng/L)

3.76 (2.66, 4.15)

4.95 (3.54, 8.34)^a

2.56 (1.41, 3.37)^{a, b}

IL12P70 (ng/L)

2.49 (1.77, 2.76)

2.15 (1.01, 3.04)

1.50 (0.58, 2.11)^a

IL17 (ng/L)

9.43 (5.68, 10.97)

6.51 (2.00, 9.96)^a

4.56 (2.00, 8.55)^{a, b}

IFNα (ng/L)

0.87 (0.39, 1.40)

1.24 (0.54, 1.24)

0.75 (0.55, 1.37)

IFNγ (ng/L)

1.37 (0.64, 2.17)

1.65 (1.00, 2.75)

1.45 (0.78, 2.25)

TNFα (ng/L)

2.67 (2.12, 3.52)

1.63 (0.78, 4.11)^a

1.22 (0.78, 2.14)^a

NLR (arbitrary unit)

2.12 (1.53, 2.88)

2.78 (1.82, 2.78)^a

2.82 (1.95, 4.20)^a

LMR (arbitrary unit)

3.86 (2.76, 4.96)

3.35 (1.98, 4.59)

3.48 (1.98, 4.67)

PLR (arbitrary unit)

120 (89, 150)

184 (113, 292)^a

163 (106, 233)^a

SII (arbitrary unit)

363 (280, 639)

571 (406, 1130)^a

695 (366, 1439)^a

PNI (arbitrary unit)

33.59 (27.28, 40.80)

39.72 (35.71, 43.62)^a

43.46 (33.21, 48.74)^a