Table 3 Correlation between carotid–femoral pulse wave velocity and clinical variables in patients undergoing coronary artery bypass grafting.

From: Serum big endothelin-1 is a significant biomarker of arterial stiffness in patients undergoing coronary artery bypass grafting

Variable

Carotid–femoral pulse wave velocity (m/s)

Simple linear regression

Multivariate linear regression

r

p value

Beta

Adjusted R2 change

p value

Age (years)

0.463

< 0.001*

0.238

0.043

0.004*

Body mass index (kg/m2)

− 0.261

0.013*

Log-operation duration (months)

0.017

0.873

Systolic blood pressure (mmHg)

0.409

< 0.001*

0.251

0.102

0.002*

Diastolic blood pressure (mmHg)

0.149

0.162

Total cholesterol (mg/dL)

0.042

0.694

Log-triglycerides (mg/dL)

− 0.062

0.561

HDL-C (mg/dL)

− 0.113

0.288

LDL-C (mg/dL)

0.051

0.632

Log-glucose (mg/dL)

−− 0.061

0.569

Log-BUN (mg/dL)

− 0.041

0.699

Log-creatinine (mg/dL)

0.067

0.530

eGFR (mL/min)

− 0.167

0.116

Log-calcium (mg/dL)

− 0.147

0.168

Phosphorus (mg/dL)

0.030

0.780

BigET-1 (pg/mL)

0.628

< 0.001*

0.533

0.387

< 0.001*

  1. Data on operation duration, triglycerides, glucose, blood urea nitrogen, creatinine, and calcium showed skewed distribution and therefore were log-transformed before analysis. Data analysis was performed using simple linear regression or multivariable linear regression with forward stepwise analysis by including the following factors: age, body mass index, systolic blood pressure, and BigET-1. BigET-1, big endothelin-1; BUN, blood urea nitrogen; CABG, coronary artery bypass grafting; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate. *p < 0.05.