Fig. 2 | Scientific Reports

Fig. 2

From: Establishment of a clinical workflow for in vivo Raman spectroscopy during head and neck cancer surgery

Fig. 2

(A) The Raman invaScope system. (B) In vivo Raman spectroscopy measurements is performed, using the fiber-optic probe (a), which is connected to the invaScope system that is equipped with a narrowband laser for excitation and a spectrometer for the data acquisition (b). The acquisition is started by pressing the foot pedal (c) and the data is displayed on the screen (d). (C) Sample collection and ex vivo Raman spectroscopy measurements on the biopsies of the measured sites. (D) Spectroscopically measured tissue samples are sent to pathology for histopathological validation. Created in BioRender. Ziller, N. (2025) https://BioRender.com/pmbzye3.

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