Table 3 Cognitive test results.

From: The deleterious effect of WHO grade II diffuse glioma on socioeconomic status as evaluated through occupation

Test name

Scores, N (%) or mean (SD)/median (range)

Normative values (where available) and interpretation of participant data (in bold)

MMSE

29.0 (1.1)/29 (27–30)

 ≥ 24 or 25/30 widely considered within normal limits (Salis et al., 2021)

All participants within normal limits

HVLT-R

HVLT-R Overall T score: 300.1 (56.1)/290 (166–398)

The overall T score had a possible range of ≤ 140 through to ≥ 560

Participants had low-to-average performance

COWAT

43.2 (11.1)/42 (21–62) (post-adjustment scores)

Mean COWAT score of 40.1 (SD = 10.5) in age- and education-matched normative data (Ruff et al., 1996)

Participants had a slightly higher overall performance compared to the normative sample

TMT

Combined A + B: 118.9 s (52.6)/99 s (74–196 s)

Normative 50th percentile (i.e., median) scores for Part A range from 23 s for the 25–34 years old group up to 38 s for the 70–74 years old group; for Part B, the equivalent 50th percentile scores range from 50 s for the 25–34 years old group to 97 s for the 70–74 years old group (Tombaugh, 2004)

At a high level, participant median Part A and B TMT scores were not markedly deranged from the normative samples

Stroop Test (Victoria version)

Stroop interference ratio

1.9 (0.4)/1.9 (1.4–2.9)

Normative data from a cohort of 272 healthy, community-dwelling adults aged 18–94 years (mean education 13 years, 64% females) living in Canada: mean (SD) of 2.0 (0.6) in the 18–39 year olds to 2.7 (1.0) in the 70–79 year olds (Troyer et al., 2006)

Overall participant performance at least in keeping with normative averages

Hayling Sentence Completion Test

Hayling Overall Scaled Score, n (%):

10 (very superior) = 0

9 (superior) = 0

8 (good) = 1 (4.8%)

7 (high average) = 1 (4.8%)

6 (average) = 16 (76.2%)

5 (moderate average) = 2 (9.5%)

4 (low average) = 1 (4.8%)

3 (poor) = 0

2 (abnormal) = 0

1 (impaired) = 0

As indicated by the key words accompanying scores (see left), the majority of participants had “average” performance

Brixton Spatial Anticipation Test

Brixton Scaled Score, n (%):

10 (very superior) = 1 (4.8%)

9 (superior) = 0

8 (good) = 1 (4.8%)

7 (high average) = 5 (23.8%)

6 (average) = 7 (33.3%)

5 (moderate average) = 2 (9.5%)

4 (low average) = 1 (4.8%)

3 (poor) = 1 (4.8%)

2 (abnormal) = 2 (9.5%)

1 (impaired) = 1 (4.8%)

As indicated by the key words accompanying scores (see left), the majority of participants had “average” performance

  1. More detailed information, including the domains evaluated by each test, the full range of outcome measures (metrics) generated for each test, and the full set of scores obtained, is provided in Supplementary Table S14.
  2. COWAT, Controlled Oral Word Association Test; HVLT-R, Hopkins Verbal Learning Test—Revised; MMSE, Mini-Mental State Examination; SD, standard deviation; TMT-A, Trail Making Test Part A; TMT-B, Trail Making Test Part B.