Fig. 2 | Scientific Reports

Fig. 2

From: Pituitary adenylate cyclase-activating polypeptide mediates bacterial endotoxin-induced fever via an effect on cyclooxygenase-2 and inflammatory cytokines

Fig. 2

Relative COX-2 gene expression in the lungs (A), liver (B), and brain (C) of Pacap+/+ and Pacap-/- mice after infusion of LPS (120 µg/kg) or saline. Tissue samples were collected at 210 min postinfusion. Number of animals in the corresponding groups are indicated in the figure. Significant differences are marked as *p < 0.05, **p < 0.01, ***p < 0.001.

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