Fig. 3 | Scientific Reports

Fig. 3

From: Pituitary adenylate cyclase-activating polypeptide mediates bacterial endotoxin-induced fever via an effect on cyclooxygenase-2 and inflammatory cytokines

Fig. 3

Serum cytokine concentrations in Pacap+/+ and Pacap-/- mice. Serum IL-1α (A), IL-1β (B), TNF-α (C), IL-6 (D), and IL-10 (E) concentrations in Pacap+/+ and Pacap-/- mice in response to LPS (120 µg/kg) or saline. Blood samples were collected at 210 min postinfusion. Number of animals in the corresponding groups are indicated in the figure. Significant differences are marked as *p < 0.05, ***p < 0.001.

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