Fig. 6 | Scientific Reports

Fig. 6

From: Green synthesis of silver nanoparticles using Magnolia alba leaf extracts and evaluating their antimicrobial, anticancer, antioxidant, and photocatalytic properties

Fig. 6

Crystal violet assay for the effects of MAgNPs and MLE on HCT-116 cells. (A) MAgNPs concentration range, from 0.1 to 500 µM in tenfold serial dilutions. (B) Selected MLE concentration range, from 25 to 250 µM. The MAgNPs depict an inhibitory bi-phasic effect on HCT-116 colorectal cancer cells. The biphasic trend showed enhanced inhibition of cells at lower concentrations and then again at higher concentrations. This suggests more than one mechanism of action which could indicate distinct cellular pathways being activated at different concentrations usually seen with antiproliferative and pro-apoptotic mechanisms of natural plant-derived bioactive molecules, or PBAMS, also known as phytochemicals. Camptothecin was 10 µM. The error bars are the standard error of the mean (SE).

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