Fig. 5
The effect of the stimulation on the response level of the cortical neurons. (a) and (b) display the frequency vs. charge 2D interpolated contour plots for LE and F1 groups, respectively. The color bar visualizes the response level (in µV). (c), (d), (e), and (f) illustrate response level changes elicited by 200 µA stimulation as a function of stimulation frequency under four phase durations (200, 500, 1000, and 1500 µs) represented by charges (40, 100, 200 and 300 nC). (g), (h), (i), and (j) show the response level evoked by 200 µA stimulation at 1, 5, 10, and 20 Hz as a function of charges (40, 100, 200, and 300 nC). In these figures, the blue circle and the purple triangle represent the LE (16 trials, 8 rats) and the F1 (8 trials, 4 rats) group, respectively. Two-way mixed ANOVA with Tukey post-hoc comparison is used for statistical analysis: *p < 0.05, **p < 0.01, ***p < 0.001. No significant difference is showed between LE and F1 groups. The blue asterisk represents the statistical significance within the LE group. The error bars represent the standard error of the mean.
