Table 3 Correlationsa between site for distant metastasis (DM) in relation to immune cell score (variable), i.e., presence of CD15+, MPO+, CD15/MPO+ immune cells, or CD15+ tumor cells (CD15+ TC) in the primary breast tumor (PT).

From: Myeloperoxidase expressing tumor associated neutrophils are associated with worse prognosis in metastatic breast cancer patients

Site of recurrence

CD15+

MPO+

CD15+MPO+

CD15+ TC

Correlation

Coefficient

P value

(2-tailed)

N

Correlation

Coefficient

P value

(2-tailed)

N

Correlation

Coefficient

P value

(2-tailed)

N

Correlation

Coefficient

P value

(2-tailed)

N

Recurrent DM vs.

de novo MBC

0.031

0.756

104

0.304

0.001**

114

0.301

0.001**

114

0.057

0.544

114

DM Lymph nodes

− 0.036

0.719

104

0.005

0.959

114

0.083

0.380

114

0.008

0.937

114

DM Ascites

0.062

0.529

104

− 0.016

0.864

114

− 0.095

0.313

114

− 0.085

0.369

114

DM Pleura

− 0.150

0.130

104

0.074

0.437

114

− 0.040

0.669

114

− 0.010

0.917

114

DM Lung

− 0.014

0.885

104

0.177

0.059

114

0.041

0.664

114

− 0.076

0.422

114

DM Liver

0.125

0.206

104

0.025

0.790

114

− 0.025

0.791

114

− 0.057

0.549

114

DM Skin

− 0.228

0.020*

104

0.094

0.318

114

0.117

0.215

114

− 0.122

0.195

114

DM CNS

0.148

0.134

104

0.157

0.095

114

− 0.082

0.386

114

0.194

0.038*

114

DM Skeleton

0.124

0.210

104

− 0.081

0.392

114

− 0.176

0.061

114

0.084

0.376

114

DM other

− 0.031

0.756

104

0.023

0.808

114

− 0.042

0.661

114

− 0.162

0.085

114

DM bone only

− 0.030

0.760

104

− 0.155

0.100

114

0.053

0.573

114

0.095

0.314

114

Number of sites

0.058

0.557

104

0.089

0.344

114

− 0.028

0.764

114

− 0.075

0.425

114

  1. a Spearman’s 2-tailed test *P < 0.05, **P < 0.01, ***P < 0.001.
  2. DM: distant metastasis.
  3. de novo MBC: metastatic disease at initial breast cancer diagnosis.