Fig. 5

ABCDai-M&M DFS performance on the independent MRD and Monitoring Validation Cohorts. A) Kaplan-Meier survival curves for ABCDai-M&M applied on the independent validation using the default probability threshold of 0.5. B) Kaplan-Meier survival curves for ABCDai-M&M applied on the independent validation using the default probability threshold of 0.5. Univariate hazard ratios are derived from Cox Proportional Hazards models, with significance assessed via log-rank tests. Events are defined as relapse or death, with time measured from the date of surgery for MRD and from therapy initiation for monitoring.