Fig. 4 | Scientific Reports

Fig. 4

From: PRELP functions via multiple interactions with intrinsically weak affinity relying on ECM anchoring and remodeling

Fig. 4

Alteration of gene expression levels by addition of recombinant PRELP. (A–B) Volcano plots from gene differential expression analysis of A549 cells treated with (A) 400 nM and (B) 2000 nM of recombinant PRELP compared with control cells. The criteria are fold change: greater than 2; q-value: less than 0.05. Significantly up- and down-regulated genes are represented as red and blue plots, respectively. (C) Gene numbers that are significantly up- or down-regulated. (D) GO cellular component analysis. Numbers of differentially expressed genes between control and 2000 nM PRELP are shown (the top 20 of up-regulated GO categories).

Back to article page