Fig. 2
From: Restoration of Oxacillin susceptibility in MRSA strains by NPPB
Antibacterial effect of the combination of oxacillin and NPPB via the disc diffusion assay. (a) MRSA ATCC 33591 bacterial suspension (100 µL of 1.5 × 108 CFU/mL) was evenly spread over the surface of the TSA plates by using a sterile cotton swab. Sterile paper discs (6 mm in diameter) were placed on the agar plate and impregnated with oxacillin (10 µg/disc), NPPB (20 µg/disc), or the combination. The agar plates were incubated at 37 °C for 24 h. oxacillin (O), NPPB (N), oxacillin + NPPB (O + N), the solvent control (0.1% DMSO, D) (b) The combination effect of oxacillin and NPPB was confirmed by measuring the diameter of the inhibition zone around the paper discs. The inhibition zone of the combination treatment was significantly larger than that of the individual treatments. ***P < 0.001 compared with the control group.
