Fig. 1
From: Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans
Thio Dosage Response in ced-1::gfp Strain. a Representative DIC, GFP, and merged fluorescence images of ced-1::gfp germlines treated with (DMSO) or 180 µM Thio for 24 h. Arrowheads indicate apoptotic cell corpses labeled by CED-1::GFP accumulation in the pachytene region of the gonad. b Quantification of apoptotic germ cell corpses per gonad across increasing Thio concentrations. Bars represent mean ± SEM. Statistical analysis was performed using one-way ANOVA with Dunnett’s multiple comparisons test (****p < 0.0001; ns, not significant). Sample size: n > 50 germlines per condition. Scale bar = 20 μm.
