Table 1 Baseline characteristics and echocardiographic parameters of the study population.
Metabolomic | Proteomic | |||||
|---|---|---|---|---|---|---|
HAPH (N = 30) | HC (N = 30) | P value | HAPH (N= 15) | HC (N=15) | P value | |
Demographic | ||||||
Male | 9.0 (30%) | 10.0 (33%) | 0.800 | 5 (33.33%) | 5 (33.33%) | 0.800 |
Age | 37 (34, 50) | 38 (34,48) | 0.900 | 45 (37,54.5) | 45 (37,51) | 0.917 |
BMI, cm/kg2 | 21.5 (19.9, 27.2) | 22.9(20.3,23.9) | > 0.900 | 21.22 (20.29,24.12) | 21.37 (20.15,23.29) | 0.934 |
Clinical feature | ||||||
SaO2,% | 82.0 (79.0, 84.0) | 83.0(81.0,86.0) | 0.300 | 82 (74,83.5) | 83 (81.5,86) | 0.297 |
SBP, mmHg | 112 (104, 120) | 110 (106, 118) | 0.506 | 113.5 ± 12.83 | 110.27 ± 9.21 | 0.434 |
DBP, mmHg | 75 (67, 80) | 75 (71, 79) | 0.846 | 74.37 ± 8.12 | 73.3 ± 6.61 | 0.696 |
HGB, g/l | 172 (160, 179) | 166(156,172) | 0.140 | 172 (163,178) | 164 (156.5,175) | 0.35 |
Echocardiographic parameters | ||||||
LVEDD, mm | 43.1 ± 4.14 | 40 ± 5 | 0.011 | 41.73 ± 4.43 | 39.4 ± 4.9 | 0.182 |
LVPWT, mm | 9 (8,9) | 9 (8,9) | 0.184 | 9 (8,9) | 9 (7.5,9) | 0.439 |
LVESD, mm | 26.7 ± 2.94 | 25.33 ± 2.41 | 0.054 | 25.73 ± 3.15 | 25.07 ± 2.63 | 0.534 |
LVEF, % | 66.4 ± 5.88 | 65.83 ± 4.68 | 0.681 | 66.4 ± 7.15 | 65.67 ± 5.46 | 0.755 |
RVOT, mm | 23.83 ± 3.64 | 23.23 ± 2.28 | 0.448 | 23.53 ± 3.91 | 23.73 ± 2.46 | 0.868 |
MPA, mm | 18 (17,18.75) | 18 (17.25,19) | 0.509 | 17.93 ± 2.05 | 17.67 ± 1.72 | 0.702 |
RVD, mm | 30.7 ± 4.26 | 24.33 ± 3.36 | < 0.001 | 30 ± 5.21 | 24.33 ± 3.35 | 0.001 |
RAD, mm | 27.5 (21.0, 33.0) | 27.0 (23.0, 33.0) | 0.800 | 28.4 ± 6.94 | 28.53 ± 5.3 | 0.953 |
LVD, mm | 35.8 ± 4.46 | 35.3 ± 4.13 | 0.654 | 35.53 ± 4.19 | 34.8 ± 4.2 | 0.636 |
LAD, mm | 25.0 (23.0, 27.0) | 26.5 (24.0, 30.0) | 0.200 | 25 (24.5,26.5) | 27 (23.5,30.5) | 0.786 |
