Fig. 1 | Scientific Reports

Fig. 1

From: Felodipine re-positioned as a neuroprotectant via improved optic nerve head blood circulation in retinal ischemic rabbits and ocular hypertensive rats

Fig. 1

Effects of intravitreal injection of felodipine on tissue blood flow (MBR-T) in the optic nerve head (ONH) in conscious rabbits. Vehicle or felodipine (7.8, 78, and 780 nmol/eye) was injected into the vitreous of the left eye of each animal, whereas the right eye remained untreated. ONH tissue blood flow was determined using laser speckle flowgraphy before injection, and 24 and 72 h after injection. ONH blood flow was expressed as a percentage of the pretreatment value (baseline). Each value represents the mean ± SEM of 1 to 4 eyes. Statistically significant differences are shown as * P < 0.05, ** P < 0.01, compared to the vehicle group at the respective timepoints (Dunnett’s multiple comparison test).

Back to article page